The number of journal papers and other articles in the medical literature that are published about ACD is growing as awareness of the condition grows within the medical community.  Below is a list of articles that we know about that have been published on ACD that are listed in publication date order.  We attempt to provide the most comprehensive database of information on ACD and therefore, appreciate any information concerning additional articles or other literature that become available.

2007

Diffuse Lung Disease in Young Children Application of a Novel Classification Scheme
Children's Interstitial Lung Disease (ChILD)Research Co-operative
Am J Respir Crit Care Med Vol 176. pp 1120-1128, 2007
Abstract and on-line source for article.    back to top

2006

Congenital Alveolar Capillary Dysplasia and associated gastrointestinal anomalies
B. Antao, M. Samuel, E. Kiely, L. Spitz, M. Malone
Fetal and Pediatric Pathology, Volume 25, Issue 3 July 2006 , pages 137 - 145
Abstract and on-line source for article.

Alveolar capillary dysplasia presenting as pneumothorax: a case report and review of literature
Pankaj G. Roy, Prerna Patel, Anitha Vayalakkad, Colene Bowker and Kokila Lakhoo
Pediatric Surgery International Published online: 30 March 2007
Abstract and on-line source for article.

Late presentation of alveolar capillary dysplasia in an infant.
Shankar, Venkat MD, MBA; Haque, Anwarul MBBS; Johnson, Joyce MD; Pietsch, John MD
Pediatric Critical Care Medicine. 7(2):177-179, March 2006
Abstract and on-line source for article.    back to top

2005

Alveolar capillary dysplasia: a six-year single center experience.
Eulmesekian P, Cutz E, Parvez B, Bohn D, Adatia I.
J Perinat Med. 2005;33(4):347-52.

Alveolar capillary dysplasia: a logical approach to a fatal disease.
Michalsky MP, Arca MJ, Groenman F, Hammond S, Tibboel D, Caniano DA.
J Pediatr Surg. 2005 Jul;40(7):1100-5.
http://www.jpedsurg.org/article/PIIS002234680500254X/abstract

Misalignment of pulmonary vessels with alveolar capillary dysplasia: association with atrioventricular septal defect and quadricuspid pulmonary valve.
Roth W, Bucsenez D, Blaker H, Berger I, Schnabel PA.
Virchows Arch. 2005 Dec 6;:1-4

Alveolar capillary dysplasia in an infant with trisomy 21.
Shehata BM, Abramowsky CR.
Pediatr Dev Pathol. 2005 Nov-Dec;8(6):696-700

Alveolar capillary dysplasia with congenital misalignment of pulmonary vessels.
Sihoe AD, Lee AT, To KF, Thung KH, Lee TW, Yim AP.
Asian Cardiovasc Thorac Ann. 2005 Mar;13(1):82-4.

Persistent pulmonary hypertension of newborn due to congenital capillary alveolar dysplasia.
Singh SA, Ibrahim T, Clark DJ, Taylor RS, George DH.
Pediatr Pulmonol. 2005 Oct;40(4):349-53.   back to top

2004

Prolonged survival in alveolar capillary dysplasia syndrome
Christoph Licht , Sabine Schickendantz, Narayanswami Sreeram, Georg Arnold, Rainer Rossi, Anne Vierzig, Udo Mennicken and Bernhard Roth
European Journal of Pediatrics Volume 163, Number 3 / March, 2004
http://www.springerlink.com/content/lw4aqepmkk235b4m/

Expanding the phenotype of alveolar capillary dysplasia (ACD).
Sen P, Thakur N, Stockton DW, Langston C, Bejjani BA.
J Pediatr. 2004 Nov;145(5):646-51

A novel association of alveolar capillary dysplasia and duodenal atresia with paradoxical dilatation of the duodenum
Noriaki Usuia, Masafumi Kamiyamaa, Shinkichi Kamataa, Akihiro Yonedaa, Yuko Tazukea, Masahiro Fukuzawaa
Journal of Ped Surgery Volume 39, Issue 12, Pages 1808-1811
http://www.jpedsurg.org/article/PIIS0022346804005718/abstract

Defective Lung Vascular Development and Fatal Respiratory Distress in Endothelial NO Synthase – Deficient Mice; A Model of Alveolar Capillary Dysplasia
Han R, Babaei S, Robb M, Lee T, Ridsdale R, Ackerley C, Post M, Stewart D
Circulation Research 2004;94:1115.
http://circres.ahajournals.org/cgi/content/full/94/8/1115    back to top

2002

Alveolar Capillary Dysplasia: a cause of Persistent Pulmonary Hypertension of the Newborn
Alameh J, Bachiri A, Devisme L, Truffert P, Rakza T, Riou Y, Manouvrier S,
Lequien P, Storme L
European Journal of Pediatrics, 161 262-266

Incidence of Alveolar Capillary Dysplasia in severe idiopathic Persistent Pulmonary Hypertension of the Newborn
Tibballs J, Chow CW
Journal of Paediatrics and Childrens Health, 38 397-400    back to top

2001

Bilateral tibial agenesis with ectrodactyly (OMIM 119100): Further evidence for autosomal recessive inheritance
Witters , K. Devriendt , Ph. Moerman , J. Caudron , C. Van Hole , J. P. Fryns
American Journal of Medical Genetics Volume 104, Issue 3 , Pages 209 – 213
http://www3.interscience.wiley.com/cgi-bin/abstract/86511289/ABSTRACT

Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins and Anterior Segment Dysgenesis of the Eye: A Report of a New Association and Review of the Literature
Merchak A, Lueder G, White F, Cole F, Sessions F
Journal of Perinatology, 21 327-330

Alveolar capillary dysplasia with antenatal anomalies mimickin trisomy 21
McGaughran J, Souter DJ, Kuschel CA
Journal of Paediatrics and Children's Health (Australia), 37 85-86

Congenital Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins Associated with Hypoplastic Left Heart Syndrome
Rabah R, Poulik JM
Pediatric and Developmental Pathology, 4 167-174    back to top

2000

Clinical approach to inhaled nitric oxide therapy in the newborn with hypoxemia
John P. Kinsella, MD, Steven H. Abman
Journal of Pediatrics June 2000, Volume 136, Number 6, p717 to p726

Urethral atresia in a neonate with alveolar capillary dysplasia and pulmonary venous misalignment
Vick, Ralph N: Owens, Thomas: Moise, Kenneth J: Chescheir, Nancy: Bukowski, Timothy P.
Urology (Online) 2000 May 1;55(5):774.
Division of Urology, University of North Carolina Hospitals, Chapel Hill, North Carolina, USA.

Congenital misalignment of pulmonary vessels and Alveolar Capillary Dysplasia: how to manage a neonatal irreversable lung disease?
Somaschini M, Bellan C, Chinaglia D, Riva S, Colombo
Journal of Perinatology, April-May 2000 20(3) 189-192

Alveolar Capillary Dysplasia. Report of a cause of prolonged life without extracorporeal membrane oxygenation (ECMO) and a review of literature
Al-Hathlol K, Phillips S, Seshia MK, Casiro O, Alvaro RE, Rigatto H
Early Human Developpment, 2000 57 85-94

Congenital misalignment of pulmonary veins with Alveolar Capillary Dysplasia causing persistent neonatal pulmonary hypertension: report of two affected siblings
Guiterrez C, Rodriguez A, Palenzuela S, Forteza C, Rossello JLD
Paediatric and Developmental Pathology, 2000 3 271-276    back to top

1999

An alternatively spliced surfactant protein B mRNA in normal human lung:disease implication
LIN Zhenwu, WANG Guirong, DEMELLO Daphne E. and FLOROS Joanna
Biochem. J. (1999) 343, 145-149
http://www.biochemj.org/bj/343/0145/3430145.pdf

Alveolar Capillary Dysplasia: an emerging syndrome
Thibeault DW, Garola RE, Killbride Howard W
Journal of Paediatrics, May 1999 134(5) 661-662

Prospective diagnosis of Alveolar Capillary Dysplasia in infants with congenital heart disease
Lane JR, Siwik E, Preminger T, Stork E, Spector M
The American Journal of Cardiology, September 1999 84 618-620

Alveolar Capillary Dysplasia: diagnostic potential for cardiac catheterisation
Hintz SR, Vincent JA, Pitlick PT, Fineman JR, Steinhiorn RH, Kim GE, Benitz WE
Journal of Perinatology, 1999 19(6) 441-446    back to top

1998

Case 3-Clinical Summary Pulmonary Hypertension in a Newborn
Warnock, ML
mw6825@itsa.uscf.edu

Neonatal hypoxemia due to misaligned pulmonary vessels with Alveolar Capillary Dysplasia
Liet JM, Joubert M, Gournay V, Godon N, Godde F, Nomballais MF, Roze JC
Arch Paediatrics, January 1998 5(1) 27-30

Familial Persistent Pulmonary Hypertension of the Newborn resulting from Misalignment of the Pulmonary Vessels (Congenital Alveolar Capillary Dysplasia)
Vassal HB, Malone M, Petros AJ, Winter RM
Journal of Medical Genetics, January 1998

Alveolar Capillary Dysplasia with and without misalignment of pulmonary veins: an association of congenital abnormalities
Garola RE, Thibeault DW
American Journal of Perinatology, February 1998 15(2) 103-107

Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the newborn: a randomised, double masked placebo controlled, dose response, multi centre study
Davidson D, Barefield ES, Kattwinkel J, Ducell G et al
Paediatrics, March 1998

Morphologic analysis of the pulmonary vascular bed in infants exposed in utero to prostaglandin synthetase inhibitors
Levin DL, Fixler DE, Morris FC, Tyson J
The Journal of Paediatrics, March 1998 92(3) 478-483

Test and Teach Number 88: Explanation and Diagnosis: Alveolar Capillary Dysplasia
Cluroe AD
Pathology, May 1998 30(155) 205-206

Urethral atresia in a neonate with Alveolar Capillary Dysplasia and pulmonary venous misalignment
Vick RN, Owens T, Moise KJ, Chescheir N, Bukiwski TP
Urology, 1 May 1998 55(5) 774

Clinical pathologic conference: a newborn infant with pulmonary hypertension
Montgomery V, Buchino JJ
The Journal of Paediatrics, July 1998

Alveolar Capillary Dysplasia with misalignment of pulmonary veins: a rare but fatal cause of neonatal respiratory failure
Kane td, Greenburg JM, Bove KE, Warner BW
Paediatric Surgery International, November 1998 14(1-2) 89-91

Alveolar Capillary Dysplasia with and without misalignment of the veins
Thibeault DW, Garola R
American Journal of Perinatology, 1998 41 270A

Pulmonary Hypertension due to Alveolar Capillary Dysplasia with misalignment of lung vessels presenting during second week of life
Arora DS, Sarvananthan R, Ahmed Z, Brownlee KG, Cullinane C
Pediatric and Developmental Pathology, 1998 457    back to top

1997

Pulmonary Pathology of Patients with Partial Liquid Ventilation
Bruch LA, Flint A, Hirschl.
Mod Pathol. 1997 May;10(5):463-8
University of Michigan Medical Center, USA

Early fetal development of lung vasculature
DE deMello, D Sawyer, N Galvin and LM Reid
American Journal of Respiratory Cell and Molecular Biology 16(5); 568

Nitric oxide inhalation therapy for an infant with persistent pulmonary hypertension caused by misalignment of pulmonary veins with Alveolar Capillary Dysplasia
Kitayama Y, Kamata, Okuyama, Usui, Sawai, Kobayashi, Fukui, Okada
Journal of Paediatric Surgery, January 1997 32 99-100

Combined therapy with inhaled Nitric Oxide and intravenous Prostacyclin in an infant with Alveolar Capillary Dysplasia
Parker TA, Ivy DD, Kinsella JP, Torielli F, Ruyle SZ, Thilo EH, Abman SH
American Journal of Respiratory and Critical Care Medicine, February 1997 155 743-746

Inhaled Nitric Oxide enhances oxygenation but not survival in infants with Alveolar Capillary Dysplasia
Steinhorn RH, Cox, Fineman, Finer, Rosenburg, Silver, Tyebkhan, Zwass, Morin
Journal of Paediatrics, March 1997 417-422

Obscure, or at least unusual paediatric lung diseases: Alveolar Capillary Dysplasia with misaligned pulmonary veins
Askin FB
Outline for presentation for Society of Paediatric Pathology, May 1997

Pathological case of the month: diagnosis and discussion. Congenital Alveolar Capillary Dysplasia and misalignment of the pulmonary vessels
Rehan V, Philips S, Fajardo C, Seshia MM
Archives of paediatric and Adolescent Medicine, November 1997 151 1163-1164

So called congenital alveolar dysplasia. Description of case
Aragona F et al
Arch De Vecchi Anat Patol, December 1997 62(2-3) 331-347 Italian

Inhaled Nitric Oxide and persistent pulmonary hypertension of the newborn
Roberts JD, Fineman JR, Morin FC, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM, Thusu KG, Zellers TM, Wylam ME, Zalavsky
New England Journal of Medicine, 1997 336 605-610

Alveolar Capillary Dysplasia: lung biopsy diagnosis, Nitric Oxide responsiveness and bronchial generation count
Sirkin W, O'Hare BP, Cox PN, Perrin D, Cutz E, Silver MM
Paediatric Pathology and Laboratory Medicine, 1997 17 125-132

Improved oxygenation in a randomised trial of inhaled Nitric Oxide for persistent pulmonary hypertension of the newborn
Wessel DL, Adatia I, Van Marter LJ, Thompson JE, Kane JW, Stark AR, Kourembanas S
Paediatrics, 1997 100(5) E7

Congenital Alveolar Dysplasia : a rare cause of persistent pulmonary hypertension
Haradia S, Lochbuhler H, Heger A, Nerlich A, Diebold J, Wiest I, Muller-Hocker J, Lohrs U
Paediatric Pathology and Laboratory Medicine, 1997 17 959-975    back to top

1996

Manouvrier-Hanu, Devisme, Farre, Hue, Storme, Kacet, Boute-Benejean, Farriaux
Genetic Counselling, November 1996 7(4) 249-255

The role of Nitric Oxide in the treatment of neonatal pulmonary hypertension.
Mariani G, Barefield ES, Carlo WA
Curr Opin Pediatr Apr, 8(2) 118-125    back to top

1995

Congenital Alveolar Capillary Dysplasia: a developmental vascular anomaly causing persistent pulmonary hypertension of the newborn
Khorsand J, Tennant R, Gillies C, Phillips AF
Paediatric Pathology, January 1995 3(2-4) 299-306

Repair of congenital diaphragmatic hernia after weaning from extracorporeal membrane oxygenation
Adolph V, Flageole H, Perreault T, Johnson A, Nguyen L, Youssef S, Guttman F, Laberge JM
Journal of Peadiatric Surgery, February 1995 30(2) 349-352

Pulmonary malformations associated with congenital cardiopathy
De Rosa N, Aliperta M
Pathologica, February 1995 87(1) 14-19 Italian

Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension
Kinsella JP, Abman SH
Journal of Paediatrics, June 1995 126(6) 853-864

Misalignment of lung vessels and Alveolar Capillary Dysplasia
Oldenburg J, Van Der Pal HJ, Schrevel LS, Blok AP, Wagenvoort CA
Histpathology, August 1995 27(2) 192-194

Timing of repair of congenital diaphramatic hernia requiring extracorporeal membrane oxygenation support
Sigalet DL, Tierney A, Adolph V, Perreault T, Finer N, Hallgren R, Laberge JM
Journal of Paediatric Surgery, August 1995 30(8) 1183-1187

Alveolar Capillary Dysplasia - A cause of persistent pulmonary hypertension unresponsive to a second course of extracorporeal membrane oxygenation
Chelliah BP, Brown D, Cohen M, Talleyrand AJ, Shen-Schwarz S
Paediatrics, December 1995 96(6) 1159-1161

Congenital misalignment of pulmonary vesels: an unusual syndrome associated with PPHN
Ng PC, Lewindon, Sui, To, Wong
Acta Paediatrics, 1995 84 349-53    back to top

1994

Misalignment of the pulmonary veins with Alveolar Capillary Dysplasia: affected siblings and variable phenotypic expression
Boggs S, Harris MC, Hoffman DJ, Goel R, McDonald-McGinn D, Langston C, Zackai E, Ruchelli E
Journal of Paediatrics, January 1994 124(1) 125-128    back to top

1993

Late presentation of misalignment of lung vessels with Alveolar Capillary Dysplasia
Adbllah HI, Karmazin N, Marks LA
Critical Care Medicine, April 1993 21(4) 628-630

Familial persistent pulmonary hypertension in two siblings with phocomelia and Alveolar Capillary Dysplasia (ACD) - a new syndrome?
Simonton SC, Chrenka BA
Modern Pathology, 1993 6 9    back to top

1992

Misalignment of Lung Vessels and Alveolar Capillary Dysplasia
Drut, Ricardo
Patologia, 1992; 30,135-137
Hospital de Ninos, La Plata, Republica Argentina

Persistent pulmonary hypertension of the newborn due to Alveolar Capillary Dysplasia
Culliane C, Cox P, Silver MM
Paediatric Pathology, July/august 1992 12(4) 499-514

Effects of Dexamethasone therapy on fibronectin and albumin levels in lung secretions of infants with bronchopulmonary dysplasia
Watts CL, Bruce MC
Journal of Paediatrics, October 1992 121(4) 597-607

An unusual cause of respiratory distress in the newborn
Wise HA et al
Journal of Urology, November 1992 108(5) 792-793

Misalignment of pulmonary veins with Alveolar Capillary Dysplasia as a cause of persistent neonatal pulmonary hypertension
Butler MW, Ursell PC, Wung JET, Stolar CJH
Neonatal Pulmonology, 1992 #1802

Natural surfactant for neonatal respiratory distress syndrome in very early premature infants: a 1992 update
Gortner L
Journal of Perinatol Medicine, 1992 20(6) 409-419

Familial persistent pulmonary hypertension of the newborn: a new autosomal recessive disease with unique histologic findings
McDonald-McGinn DM, Ruchelli E, Uri A, Langston C, Bowen F, Harris MC, Polin R, Karmazin N, Goel R, Boggs S, Hoffman D, Zackai E
American Journal of Human Genetics, 1992 51(Supplement) A102

1991

Misalignment of the pulmonary veins with Alveolar Capillary Dysplasia
Langston C
Paediatric Pathology, 1991 11 163-170    back to top

1990

Neonatal hyperoxia alters the pulmonary alveolar and capillary structure of 40 day old rats
Randall SH, Mercer RR, Young SL
American Journal of Pathology, June 1990 136(6) 1259-1266

Primary Alveolar Capillary Dysplasia
Newman B, Yunis E
Paediatric Radiology, 1990 21(1) 20-22    back to top

1989

Misalignment of the lung vessels and Alveolar Capillary Dysplasia: a cause of persistent pulmonary hypertension
Cater G, Thibeault DW, Beatty EC, Kilbride HW, Huntrakoon M
Journal of Paediatrics, February 1989 114 293-300    back to top

1986

Misalignment of lung vessels: a syndrome causing persistent neonatal pulmonary hypertension
Wagenvoort CA
Human Pathology, July 1986 17(7) 727-730    back to top

1984

The structural basis of PPHN
Geggel RL, Reid LM
Clinical Perinatology, October 1984 11(3) 525-549

Familial persistent pulmonary hypertension
Shohet I, Reichman B, Schibi G, Brish M
Archives of Disease in Childhood, 1984 59 783-785    back to top

1982

The radial alveolar count method of Emery and Mithal: a reappraisal 2- Intrauterine and early postnatal lung growth
Cooney TP, Thurlbeck WM
Thorax, 1982 37 580-583    back to top

1981

Congenital Alveolar Capillary Dysplasia - an unusual cause of respiratory distress in the newborn
Janney CG, Askin FB, Kuhn C
American Journal of Clinical Pathology, November 1981    back to top

1978

Fetal hypertension and the development of increased pulmonary vascular smooth muscle: A possible mechanism for persistent pulmonary hypertension of the newborn infant
Daniel L. Levin, et. al
The Journal of Pediatrics 1978;92:2:265-269
Department of Pediatrics, The University of Texas Health Science Center at Dallas, Dallas, TX

Morphologic analysis of the pulmonary vascular bed in infants exposed in utero to prostaglandin synthetase inhibitors.
Levin DL, Fixler DE, Morriss FC, Tyson J.
The Journal of Pediatrics. March 98, 92 (3); 478-483.
Dallas, Texas, USA

A simple technique for measuring alveolar CO₂ in infants
Dumpit FEM, Brady JP
Journal of Applied Physiology, October 1978 45 648-650    back to top

1976

Persistent fetal circulation: newly recognised structural features
Haworth SG, Reid L
Journal of Paediatrics, April 1976 88 614-620

Congenital Alveolar Capillary Dysplasia of the lung: critical review and personal cases
De Turris P et al
Patholigica, May 1976 68(979-980) 211-221 Italian    back to top

1975

Proceedings: Congenital Alveolar Lung Dysplasia
Munterfering H, et al.
Verh Dtsch Ges Pathol. 1975 Jan 1; 59: 576   back to top

1973

Unilateral congenital dysplasia of lung associated with vascular abnormalities
Hislop A, Sanderson M, Reid L
Thorax, 1973 28 435-441    back to top

1972

An Unusual Cause of Respiratory Distress in a Newborn
Wise, HA 2nd, et al.
J Urol. Nov,1972; 108 (5): 792-793.
Ohio State University Hospital   back to top

1971

The Effects of Maternal Hypoxia and Hyperoxia Upon the Neonatal Pulmonary Vasculature
Stanley J. Goldberg, et al.
Pediatrics 1971;48:528-533
University of Arizona, College of Medicine, Department of Pediatrics, Tucson, Arizona   back to top

1966

Congenital Alveolar Capillary Dysplasia of the lung in newborn infant
Habanec B
Cesk Pediatr, March 1966 21(3) 256-258 Czech    back to top

1965

Interstitial lung disease (alveolar-capillary block)
Read J
New Zealand Medical Journal, December 1965 64(400 Supplement) 96    back to top

1948

Congenital Alveolar Dysplasia of the lungs
MacMahon HE
American Journal of Pathology, 1948 24 919-930    back to top